Biotech Scan
Biotech Scan
Biotech rotation in progress — ALNY recovered from RSI 25 to 49, MRNA surged +18% in 7 days, LEGN still collapsed at RSI 8. Gene editing broadly weak. Large pharma (LLY, GILD, BIIB) cooling from overbought levels.
Quick Snapshot
| Signal | Reading |
|---|---|
| Overall | 🟡 MIXED — Recovery underway in mRNA/RNAi, gene editing lagging, large pharma pulling back |
| Key insight | MRNA +18% 7D recovery trade live; LEGN RSI 8 still collapsed (2nd week); LLY -3% 7D as GLP-1 trade cools |
Price Table (Validated 2026-02-22)
| Stock | Price | RSI | SMA20 | vs SMA | 7D | 30D | Signal |
|---|---|---|---|---|---|---|---|
| CRSP | $53.46 | 58 | $51.66 | +3.5% | +0.7% | -2.3% | 🟡 Neutral |
| BEAM | $27.92 | 38 | $28.79 | -3.0% | +2.3% | -21.2% | 🟡 Weak |
| EDIT | $1.76 | 35 | $1.96 | -10.2% | -2.8% | -20.7% | 🔴 Breakdown |
| NTLA | $12.64 | 46 | $12.82 | -1.4% | +6.5% | -9.9% | 🟡 Recovering |
| ALNY | $336.19 | 49 | $336.99 | -0.2% | +6.9% | -8.0% | 🟡 Recovering |
| LEGN | $17.20 | 8 | $19.40 | -11.3% | +3.2% | -27.1% | 🔴 Capitulation |
| MRNA | $49.87 | 67 | $44.23 | +12.8% | +18.1% | +0.1% | 🟠 Near Overbought |
| BNTX | $110.14 | 43 | $110.69 | -0.5% | +4.0% | -6.7% | 🟡 Neutral |
| LLY | $1,009.52 | 47 | $1,035.59 | -2.5% | -2.9% | -6.2% | 🟡 Below SMA |
| GILD | $151.40 | 63 | $147.11 | +2.9% | -2.3% | +17.3% | 🟡 Cooling |
| BIIB | $192.03 | 62 | $185.87 | +3.3% | -2.3% | +11.3% | 🟡 Cooling |
Tier Analysis
Tier 1 — Recovering / Momentum (MRNA, ALNY, NTLA)
MRNA RSI jumped from 33 to 67 in one week — +18% move likely catalyst-driven. Approaching overbought; do not chase. ALNY recovered from RSI 25 to 49 — RNAi thesis intact, back near SMA. NTLA reversed from RSI 36 to 46, +6.5% 7D. Gene editing tentative bounce forming.
Tier 2 — Stable / Holding (CRSP, BNTX, LLY, GILD, BIIB)
CRSP RSI 58 above SMA — best positioned in gene editing. BNTX neutral near SMA after +4% bounce. LLY RSI 47 but now -2.5% below SMA; GLP-1 premium compressing. GILD and BIIB cooling from RSI 72 highs — RSI retreated to 63/62, still holding above SMA. Normal decompression, not breakdown.
Tier 3 — Weak / Broken (BEAM, EDIT, LEGN)
BEAM -21% 30D, RSI 38, still below SMA — no recovery signal. EDIT -21% 30D, RSI 35, -10% below SMA — continued deterioration. LEGN RSI 8 for second consecutive week — extreme capitulation, company-specific collapse, avoid unless thesis understood.
Entry Zones
| Stock | Zone | RSI Trigger | Conviction | Notes |
|---|---|---|---|---|
| 🟡 ALNY | $325-$340 | RSI < 45 | MEDIUM | RNAi leader, recovered to SMA — watch for hold confirmation |
| 🟡 LLY | $990-$1,010 | RSI < 45 | MEDIUM | GLP-1 king pulling back to SMA zone, long-term thesis intact |
| 🟡 BNTX | $105-$112 | RSI < 40 | LOW | mRNA recovery play, needs catalyst |
| 🟡 NTLA | $11.50-$12.50 | RSI < 40 | LOW-MEDIUM | Gene editing recovery, smaller position |
| 🔴 LEGN | Avoid | — | SPECULATIVE | RSI 8 two weeks running, unknown catalyst, high risk |
Action Matrix
| Action | Stocks | Why |
|---|---|---|
| 🔒 HOLD | CRSP, ALNY, GILD, BIIB | Holding above SMA, recovering or stable |
| 🔍 WATCH | LLY, BNTX, NTLA | Pulling back or bouncing — wait for RSI confirmation |
| ⚠️ AVOID | MRNA | RSI 67, +18% 7D — do not chase, extended |
| ⚠️ AVOID | BEAM, EDIT | Continued weakness, no reversal signal, -20%+ 30D |
| ⚠️ AVOID | LEGN | RSI 8 (second week), broken, high risk |
Key Discoveries
| Discovery | Implication |
|---|---|
| MRNA +18% in 7 days, RSI 33→67 | Likely single catalyst — do not read as sector reversal |
| LEGN RSI 8 two consecutive weeks | Company-specific collapse, not sector contagion |
| GILD/BIIB RSI cooling from 72 to 63/62 | Healthy decompression, not breakdown — defensive biotech still intact |
| LLY now -2.5% below SMA | GLP-1 premium compressing — watch $990 as next support |
Open Questions
Related
10 eventsNo direct external sources are attached to this read.