Biotech capital-cycle expression ladder

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Biotech capital-cycle expression ladder

Biotech capital-cycle expression ladder — 2026-08-24

Internal rung-authoring receipt for the first conviction-pipeline lanes. The durable setup remains the perspective's own rule: quality tools/CROs enter on a support reset that holds; post-exhaustion mid-caps require a higher low, a reclaim, and volume confirmation. A numeric touch only asks for a verdict. The shape legs still have to be present before an in-zone verdict can convert.

Fresh tape

Tier Ticker Aug 21 close RSI 20-day 50-day 200-day Relative volume Rung
Quality tools DHR $218.85 68.3 $202.86 $195.43 $202.97 1.07x Wait for the $210.39 volume shelf; do not chase the current extension.
Post-exhaustion VKTX $33.89 47.9 $33.66 $35.08 $33.72 0.78x Higher low, then 50-day reclaim on confirming volume.
Post-exhaustion AGIO $33.09 44.7 $33.26 $35.56 $30.93 0.47x Higher low, then 50-day reclaim on confirming volume.

TXG ($65.12, RSI 74.0, +38.4%/30d) remains an extended pass. ABSI has reset to RSI 56.6 but is already above its 20-day without confirming volume (0.86x), so it also stays a pass rather than inheriting either VKTX or AGIO's receipt.

Sources

  • Setup rules and tier membership: research/perspectives/2026-06-04-biotech-capital-cycle/README.md.
  • Settled price, RSI, averages, shelves, returns, and relative volume: research/market-engine/data/summaries/biotech-capital-cycle.json (latestDate: 2026-08-21).
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