Biotech Scan

Scan

Biotech Scan

raw scan snapshot — prices as of scan date, not live 60 rows · screens, not recommendations

Biotech ETFs (XBI/IBB) are ripping to near-ATH with RSI 74-76 and 35%+ above VWAP — sector is broadly extended; LABU (3x) and MRNA are parabolic; the only clean entries are the mid-tier basing names (AMGN, CRSP, GILD, NVO) and selective speculative names off lows.

Source: biotech-scan.json. Latest bar 2026-06-26 (VRTX stale at 2026-06-25).

Quick Snapshot

Signal Reading
Overall 🟠 Sector broadly extended — ETFs at/near ATH (XBI RSI 76, IBB RSI 74, LABU RSI 77); MRNA +82% vs VWAP (parabolic); ABBV at ATH; ILMN/INCY/KYMR/PTGX led this week
Leaders ABBV (RSI 76.6, ATH, +18% 30D, +22% vs VWAP); RARE (RSI 75.7, +31.6% 30D, +15% vs VWAP); XBI (RSI 76.2, near ATH, +35.6% vs VWAP); MRNA (RSI 71.4, +41.3% 30D, +82% vs VWAP)
Laggards SRPT (RSI 49.2, -9.5% 7D, collapse DC, -14.4% vs SMA200); ISRG (RSI 41.6, -10.6% 3M, collapse DC, -17.3% vs SMA200); REGN (RSI 50.7, -14.1% 3M, strong-down DC)
Froth flags LABU +130.5% vs VWAP (truly parabolic); MRNA +82% vs VWAP; KYMR +51.1% vs VWAP; PTGX +49.2% vs VWAP; AMAT/AMD context: biotech is now as extended as semis on a VWAP-basis
Key insight Biotech sector re-rate is real and broad (XBI +30% 3M, IBB +17% 3M) but all the ETF upside is priced near-term; the cleanest EOW entries are the non-frothy mid-caps: AMGN/GILD/NVO basing + spec names NTLA/COGT off big-volume runs

Price Table

Stock Price RSI vs SMA20 7D% 30D% 3M% 52wkHi% Trend Signal
ISRG $404.70 41.6 -1.6% -0.3% -3.3% -10.6% -33.0% strong-down DC ❌ Broken
SRPT $16.85 49.2 +2.8% -9.5% +1.0% -15.6% -33.5% strong-down DC ❌ Broken
REGN $632.90 50.7 +2.8% +3.3% +0.8% -14.1% -22.9% strong-down DC ❌ Avoid
ALNY $291.37 49.4 +0.1% +4.9% -1.4% -8.2% -41.2% strong-down DC ❌ Broken
NKTR $63.65 48.4 +4.5% -4.0% -2.7% -7.3% -41.6% weak-down GC ⚠️ Avoid
DXCM $70.14 48.9 -3.8% -1.8% -0.2% +12.7% -22.1% up DC 🔍 Watch
EDIT $2.85 53.4 +4.0% -1.1% -20.2% +27.8% -37.2% weak-down GC ⚠️ Caution
LEGN $28.69 45.3 -10.2% 0.0% +0.7% +70.8% -36.7% strong-up GC 🔍 Watch (pullback after run)
BNTX $91.22 51.6 +1.5% -0.6% -1.9% +6.5% -26.4% strong-down DC ⚠️ Avoid
GILD $127.88 51.7 +1.3% -0.1% -3.7% -4.1% -18.7% down GC 🔍 Watch (basing)
RXRX $3.52 58.3 +5.5% +6.7% +11.0% +19.7% -51.0% weak-up DC 🔍 Watch
CRSP $54.92 57.4 +3.8% -0.8% +2.6% +20.0% -30.0% weak-up DC 🔍 Watch
MDT $80.98 55.2 +2.0% +2.5% +6.6% -7.1% -23.8% weak-up DC 🔍 Watch
AMGN $358.33 62.3 +3.9% +3.2% +6.6% +3.5% -8.4% strong-up GC 📈 Accumulate
BEAM $34.81 61.1 +10.0% -4.8% +9.2% +56.9% -5.6% strong-up GC 🔍 Watch (extended)
DNA $10.25 66.7 +16.7% +8.7% +17.7% +72.9% -41.7% up DC 🔍 Watch
IQV $191.14 63.7 +5.7% +13.6% +15.4% +16.7% -22.6% weak-up DC 🔍 Watch
BMRN $59.00 64.6 +5.1% +3.7% +12.6% +9.0% -11.0% up DC 🔒 Hold
A $136.01 63.9 +2.9% +7.4% +17.4% +23.7% -15.1% up DC 🔒 Hold
TMO $513.03 66.5 +6.9% +10.1% +12.6% +8.5% -20.3% weak-up DC 🔒 Hold
NVO $48.07 68.2 +8.5% +5.2% +7.9% +38.3% -33.1% up DC 📈 Accumulate
COGT $38.10 70.1 +12.2% +7.5% +10.4% +5.5% -12.9% strong-up GC 🔒 Hold
NTLA $16.68 65.7 +17.1% +2.3% +24.1% +34.8% -41.0% strong-up GC 🔍 Watch
DHR $196.19 69.3 +7.3% +10.1% +13.3% +8.1% -19.2% weak-up DC 🔒 Hold
BIIB $216.03 69.3 +9.3% +2.8% +9.7% +17.5% -0.9% strong-up GC 🔒 Hold
VRTX‡ $480.18 69.2 +6.8% +4.8% +10.2% +5.8% -5.5% up DC 🔒 Hold
INCY $113.75 68.9 +11.1% +5.9% +16.9% +26.0% -1.6% strong-up GC 🔒 Hold
IONS $81.18 70.8 +8.2% +5.2% +6.1% +12.5% -6.4% up DC 🔒 Hold
ILMN $176.55 67.5 +6.8% +11.0% +17.6% +50.0% -3.4% strong-up GC 🔒 Hold (+43% vs VWAP)
LLY $1,208.12 72.7 +7.7% +2.7% +11.6% +37.8% -0.6% strong-up GC ⚠️ Extended (ATH, +33.6% vs VWAP)
MRNA $67.27 71.4 +25.9% +1.8% +41.3% +35.7% -2.9% strong-up GC ⚠️ PARABOLIC (+82% vs VWAP)
PTGX $121.88 71.2 +12.8% +6.1% +19.2% +23.2% -3.5% strong-up GC ⚠️ Extended (+49.2% vs VWAP)
KYMR $108.12 70.2 +25.2% +16.3% +32.3% +38.3% -16.9% strong-up GC ⚠️ Extended (+51.1% vs VWAP — parabolic flag)
RARE $30.77 75.7 +22.3% +4.3% +31.6% +58.8% -27.4% up DC ⚠️ Extended (+15.4% vs VWAP)
ABBV $253.35 76.6 +12.1% +7.3% +17.6% +22.0% 0.0% up DC ⚠️ Extended (ATH, +18.1% vs VWAP)
IBB $187.36 74.1 +8.5% +4.7% +10.3% +16.8% -0.7% strong-up GC ⚠️ Extended (+17.3% vs VWAP, near ATH)
IBBQ $32.23 73.8 +8.2% +3.5% +9.3% +16.9% -0.4% strong-up GC ⚠️ Extended (+15.1% vs VWAP, near ATH)
XBI $155.38 76.2 +13.2% +5.0% +15.7% +30.1% -0.3% strong-up GC ⚠️ Extended (+35.6% vs VWAP, near ATH)
LABU $276.16 77.1 +41.3% +15.1% +48.5% +99.4% -1.1% strong-up GC 🔴 PARABOLIC (+130.5% vs VWAP)

VRTX stale (2026-06-25 bar).

Tier Analysis

Collapsing / Broken (RSI < 52, DC, below SMA200)

  • ISRG ($404.70, RSI 42) — Collapse, DC, -17.3% vs SMA200, -33% from ATH. Surgical robotics overhang (J&J Ottava / Medtronic Hugo). No entry.
  • SRPT ($16.85, RSI 49) — Sarepta: strong-down, DC, -14.4% vs SMA200, -9.5% 7D on 4x normal volume. Duchenne setback price action. Avoid.
  • REGN ($632.90, RSI 51) — Regeneron: strong-down, DC, -14.1% 3M, -9.2% vs SMA200. Dupixent/eylea concerns. Avoid.
  • ALNY ($291.37, RSI 49) — Alnylam: strong-down, DC, -21.3% vs SMA200, -41.2% from ATH. SiRNA platform de-rated. Avoid.
  • BNTX ($91.22, RSI 52) — BioNTech: strong-down, DC, -8.1% vs SMA200. mRNA franchise hollowing out post-COVID. Avoid.
  • NKTR ($63.65, RSI 48) — Nektar: weak-down, -41.6% from ATH. Pulled back -4% 7D off a prior big 3Y run. Wait.

Neutral / Basing (RSI 53–65)

  • GILD ($127.88, RSI 52) — Gilead: basing, GC intact, -0.2% vs SMA200. Flat week but technically on the SMA200 — cleanest mid-cap watch in the scan.
  • CRSP ($54.92, RSI 57) — CRISPR: weak-up, DC, -1.1% vs SMA200, +20% 3M. Below the 200 but basing. Gene-editing re-rate ongoing.
  • AMGN ($358.33, RSI 62) — Amgen: strong-up, GC, +8.7% vs SMA200, +6.6% 30D. Cleanest large-cap accumulate in the scan — not extended.
  • NVO ($48.07, RSI 68) — Novo Nordisk (ADR): GLP-1 recovery, +38.3% 3M, +2.9% vs SMA200, +1.3% vs VWAP — not frothy despite the run. DC still in place. Accumulate on any SMA20 retest.
  • TMO ($513.03, RSI 67) — Thermo Fisher: weak-up, DC, -2.3% vs SMA200, +12.6% 30D. Lab-tools bouncing; still below SMA200 — wait for reclaim.
  • DHR ($196.19, RSI 69) — Danaher: weak-up, DC, -3.6% vs SMA200, +13.3% 30D bounce. Same pattern as TMO — relief rally not yet a reclaim.

Momentum / Leading (RSI 65–74)

  • ILMN ($176.55, RSI 68) — Illumina: strong-up, GC, +37.4% vs SMA200, +11% 7D, +50% 3M. Big breakout. Extended at +43% vs VWAP but thesis is turning; hold.
  • BIIB ($216.03, RSI 69) — Biogen: strong-up, GC, +22.6% vs SMA200, near ATH. Alzheimer drug re-rate holding. Hold.
  • INCY ($113.75, RSI 69) — Incyte: strong-up, GC, +16.9% vs SMA200, near ATH (-1.6%). JAK inhibitor franchise. Hold.
  • NTLA ($16.68, RSI 66) — Intellia: strong-up, GC, +22.9% vs SMA200, +24.1% 30D. In-vivo gene-editing momentum.

Extended / Parabolic (RSI > 71)

  • ABBV ($253.35, RSI 77) — AbbVie: at ATH, +17.6% 30D, +18.1% vs VWAP. Don't chase.
  • MRNA ($67.27, RSI 71) — Moderna: +82% vs VWAP (poc at $25.22 — price nearly 3x above the long-term VWAP). +41.3% 30D. The most extended large-cap name.
  • KYMR ($108.12, RSI 70) — Kymera: +51.1% vs VWAP (parabolic); +32.3% 30D, 3.6x avg volume this week. Clinical-stage; frothy.
  • PTGX ($121.88, RSI 71) — Protagonist: +49.2% vs VWAP, near ATH, +19.2% 30D.
  • XBI ($155.38, RSI 76) — ETF: +35.6% vs VWAP, near ATH. Don't add to sector ETF here.
  • LABU ($276.16, RSI 77) — 3x Biotech: +130.5% vs VWAP — parabolic leveraged ETF. If owned, protect gains; do not initiate.

Entry Zones

Stock Price Zone RSI 30D% Setup
AMGN $358.33 <$350 (SMA20 retest) 62.3 +6.6% Large-cap basing; GC; +8.7% vs SMA200; not extended (+10.9% vs VWAP)
NVO $48.07 <$46 (SMA20 retest) 68.2 +7.9% GLP-1 recovery; +38.3% 3M; +2.9% vs SMA200; +1.3% vs VWAP = not frothy
GILD $127.88 <$126 (SMA20 support) 51.7 -3.7% Basing on SMA200; GC; +2.5% vs VWAP; oversold-adjacent, cleanest base setup
NTLA $16.68 <$16 65.7 +24.1% In-vivo gene editing; GC; +22.9% vs SMA200; +23.2% vs VWAP — not parabolic
ILMN $176.55 <$165 (SMA20) 67.5 +17.6% Breakout confirmed; GC; +37.4% vs SMA200; only add on pullback to SMA20

Action Matrix

Action Stocks Why
🔒 HOLD BIIB, INCY, AMGN, IONS, ILMN, COGT, BMRN, A, IQV, TMO, DHR Uptrends / breakouts intact; thesis active; don't sell strength
📈 ACCUMULATE AMGN, NVO, GILD Not extended; basing on or near SMA200; best risk/reward in sector
🔍 WATCH NTLA, CRSP, LEGN, RXRX, DXCM, DNA Biotech speculation — wait for volume + confirmation; don't front-run
⚠️ EXTENDED / DON'T CHASE ABBV, LLY, MRNA, KYMR, PTGX, XBI, IBB, IBBQ, RARE RSI 70-77; 15-82% above VWAP; near-ATH; fully priced short-term
🔴 PARABOLIC — PROTECT LABU +130.5% vs VWAP, RSI 77; leveraged ETF at risk of violent reversal; trail stop if owned
❌ BROKEN / AVOID ISRG, SRPT, REGN, ALNY, BNTX Collapse/strong-down regimes; DC; below SMA200; structural de-rates

What Changed This Week (EOW)

  • Biotech ETFs went parabolicXBI +5% 7D (RSI 76, near ATH, +35.6% vs VWAP), IBB +4.7% 7D (RSI 74, near ATH). The sector re-rate that started with MRNA/LLY has now broadened into the ETFs themselves; buying the ETF here is chasing.
  • ABBV broke to ATH — RSI 77, +7.3% 7D, +17.6% 30D, +18.1% vs VWAP. AbbVie is the week's standout large-cap print; confirms the biotech/pharma rotation bid.
  • KYMR +16.3% 7D — The week's top gainer in scan; +51.1% vs VWAP is a froth flag; clinical catalyst-driven.
  • ILMN +11% 7D — Illumina confirmed breakout; +37.4% vs SMA200 and +50% 3M; now in "hold" territory (extended to add, but don't sell).
  • ISRG still collapsing — RSI 42, -10.6% 3M, -33% from ATH; DC confirmed; focused medtech remains the sector's structural loser.
  • MRNA froth deepens — +41.3% 30D, +82% vs VWAP; poc at $25.22; the stock has tripled off its base but is trading far above any reasonable VWAP anchor. Hold if owned, don't initiate.

Key Discoveries

Discovery Implication
XBI/IBB both >35% vs VWAP at near-ATH Sector ETF level is not an entry — the broad re-rate is fully priced in the ETFs; alpha is now stock-specific
MRNA +82% vs VWAP with poc at $25 The "price of control" is $25 — this run is momentum-driven, not mean-reverting; any selloff could be deep
AMGN/NVO are the only large-caps not extended vs VWAP Two quality accumulate setups in a fully extended sector

Mistakes (Don't Repeat)

Mistake Lesson
Chasing XBI/IBB on sector breakout At +35% vs VWAP and RSI 76, the ETF buy is a late-cycle momentum trade, not a thesis entry
Treating ISRG's "intact" thesis tag as a buy signal collapse + DC + below SMA200 = broken trend; thesis tag ≠ entry

Open Questions

  • ILMN at +43% vs VWAP: does the +50% 3M run have a second leg, or does it mean-revert to the SMA20 ($165) first?
  • MRNA +82% vs VWAP: what's the catalyst that could hold this level? Without a clinical update, gravity is brutal.
  • KYMR/PTGX: are these clinical catalyst names or just sector-beta levered to the XBI run?
10 events

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